230 Human Physiology (5) Fundamentals of human physiology, primarily from the perspective of cellular and organ-system interactions.
Contact Hour Distribution: 4 hours and 1 lab.
Credit Restriction(s): May not be applied toward the biochemistry and cellular and molecular biology concentration.
(RE) Prerequisite(s): Chemistry 110 or Chemistry 130.
306 Genetics and Society (3) Introduction to genetics, anthropology, and evolution with emphasis on their implications for human society. (Same as Anthropology 304.)
310 Physiological Chemistry (4) Biochemical principles underlying physiological events in animals. Metabolism of carbohydrates, lipids, proteins, and nucleic acids. Role of vitamins and minerals as coenzyme and prosthetic groups. Action of drugs and hormones. (Same as Nutrition 310.)
Credit Restriction(s): Not available for credit if credit has been previously received for Biochemistry and Cellular
and Molecular Biology 401 or 410 or 420. Credit may not be applied toward the biochemistry and cellular and
molecular biology concentration.
(RE) Prerequisite(s): Biology 140 or Biochemistry and Cellular and Molecular Biology 230.
(DE) Prerequisite(s): Chemistry 100 and 110 or Chemistry 120 and 130.
320 Physiology of Reproduction and Lactation (3) (See Animal Science 320.)
321 Introductory Plant Physiology (4) Cell and organismal physiology of plants, metabolic processes, water relations, mineral nutrition, morphogenesis. Effects of age, light, natural rhythms, temperature, and other environmental factors on plant growth.
(RE) Prerequisite(s): Chemistry 120 and Chemistry 130.
(DE) Prerequisite(s): Biology 101 and 102 or Biology 130 and 140.
330 Mechanisms of Development (3) A survey course on cellular and molecular basis of embryonic development, differentiation via transcription, RNA processing and translation, sex determination in humans.
(RE) Prerequisite(s): Biology 140 and Biology 240.
Comment(s): Intended for biology majors in the biochemistry and cellular and molecular biology concentration, but
also open to biology majors in other concentrations.
401 Biochemistry-Molecular Biology I (4) First semester of a two-course sequence providing in-depth coverage of biochemistry and molecular biology. Covers amino acid structure and chemistry, protein structure and chemistry, protein folding, enzyme behavior and function, reaction mechanisms, catabolism and energy transfer, synthetic metabolism including photosynthesis, and protein transport.
(RE) Prerequisite(s): Biology 240 and Chemistry 360.
(DE) Prerequisite(s): Chemistry 350 and Chemistry 369.
Comment(s): Intended for biology majors in the biochemistry and cellular and molecular biology concentration, but
also open to biology majors in other concentrations.
402 Biochemistry-Molecular Biology II (4) Second semester of a two-course sequence providing in-depth coverage of biochemistry and molecular biology. Covers structure of DNA and RNA, experimental methods of analyzing nucleic acids, mechanisms of RNA and protein synthesis, mechanisms of DNA replication, repair and recombination, chromosome structure and function, regulation of gene expression, genome structure and genomics, and mechanisms of biological regulation.
(RE) Prerequisite(s): 401.
Comment(s): Intended for biology majors in the biochemistry and cellular and molecular biology concentration, but
also open to biology majors in other concentrations.
403 Advanced Genetics Laboratory (3) Experiments illustrating methods in modern genetics, including techniques in classical, cyto-molecular and developmental genetics. Using model organisms, especially Drosophila and mouse.
Contact Hour Distribution: Laboratory and lecture.
(RE) Prerequisite(s): Biology 240 and Chemistry 360.
404 Plant Molecular Biology (3) Introduction to current research approaches and methodologies in plant developmental biology and molecular genetics.
Contact Hour Distribution: Laboratory and lecture.
(RE) Prerequisite(s): Biology 240.
409 Perspectives in Biochemistry and Cellular and Molecular Biology (3) Current issues in biochemistry, cell biology and molecular biology. Emphasis on current developments and their applications, societal and economic impacts, and moral and ethical implications. An oral presentation and a referenced library-research essay are required. A capstone course. Writing-emphasis course. (WC)
(RE) Prerequisite(s): 401 or 402.
Recommended Background: 9 additional hours of biochemistry and cellular and molecular biology or related
courses.
Registration Restriction(s): Minimum student level – senior.
411 Advanced Cellular Biology (3) Cellular structure and function at the molecular and supramolecular level. Topics include protein structure and function, membrane structure and function, signal transduction and cell regulation, mitosis and the cell cycle, cytoskeleton and cell motility, cell-cell interactions and tissues.
(RE) Prerequisite(s): 401.
415 Foundations in Neurobiology (3) Basic nerve cell physiology, nervous system organization, sensory and motor systems, neural basis of behavior, and nervous system development and plasticity.
(RE) Prerequisite(s): Biology 140 and Physics 222.
416 Neurobiology Laboratory (2) Experiments designed to illustrate concepts of modern neurobiology using electrophysiological, historical, and behavioral neurobiological techniques.
(RE) Prerequisite(s): 415.
419 Cellular and Comparative Biochemistry Laboratory (2) Experiments with enzymes, nucleic acids, and membranes and organelles. Chromatography, kinetics, hybridization, sequencing, and immunochemical methods.
(RE) Prerequisite(s): 401.
420 Advanced Topics in Biochemistry and Cellular and Molecular Biology (3) Selected topics of current research interest, e.g., allosteric theory and control of protein function, immunochemistry, regulation of gene expression, bioenergetics, etc. Emphasis on original literature and the experimental basis of current knowledge. Historical background, societal impact, ethical and moral implications, and future development of technologies. Written reports required. Writing-emphasis course.
(RE) Prerequisite(s): 401.
421 Cell and Tissue Structure and Function (4) Study of animal cells and tissues at light and electron microscope levels.
Contact Hour Distribution: 2 hours and 2 labs.
(RE) Prerequisite(s): Biology 140.
440 General Physiology (3) Principles of cellular and organ-system animal physiology.
(RE) Prerequisite(s): Biology 140 and Chemistry 360.
Recommended Background: Physics 221 and 222.
452 Independent Research in Biochemistry (1-6) Special experimental problems under direction of a staff member.
Repeatability: May be repeated. Maximum 12 hours.
(RE) Corequisite(s): 401 and 419.
457 Honors Thesis (1-3) Written preparation and oral presentation of faculty-supervised student research conducted in 452 or equivalent.
Repeatability: Not repeatable. May be taken once for 1-3 hours.
Credit Restriction(s): Credit may not be applied toward the biochemistry and cellular and molecular biology
concentration.
(RE) Prerequisite(s): 452.
Registration Restriction(s): Biological sciences major/honors biochemistry and cellular and molecular biology
concentration.
459 Biophysical Crystallography (3) Theories and practices of X-ray diffraction, neutron diffraction and neutron scattering to elucidate the structure of nucleic acids, proteins, nucleosomes, ribosomes and viruses. Application of 3-D structures in designing drugs against AIDS, cancer, cardiac disease and neurodegenerative disorders.
Recommended Background: 401, or two 300-level chemistry courses or Physics 240 or consent of instructor.
460 Cancer Biology (3) Fundamental mechanisms of cancer formation and therapy, including cell cycle, cancer epidemiology cancer pathology, oncogenes, tumor suppressor genes, DNA repair, and metastasis.
Recommended Background: Biology 240 or consent of instructor.
465 Human Genetics (3) Genetic and molecular principles and problems of human inheritance.
(RE) Prerequisite(s): Biology 240.
471 Biophysical Chemistry (3) Physicochemical principles with applications to biological systems. Thermodynamics, chemical equilibrium, solution chemistry, transport, electrochemistry, kinetics, enzyme catalyzed reactions. (Same as Chemistry 471.)
(DE) Prerequisite(s): Chemistry 350 and 360 and 369; Biology 130 or 102.
Recommended Background: Calculus.
480 Physiology of Exercise (3) (See Exercise Science 480.)
481 Biophysical Chemistry (3) Physicochemical principles with applications to biological systems. Elementary quantum chemistry, interactions of light with biological molecules, optical and magnetic spectroscopy, light scattering, case studies of selected macromolecules. (Same as Chemistry 481.)
(DE) Prerequisite(s): Chemistry 350, 360, 369 and Biology 130 or 102.
Recommended Background: Calculus.
492 Off-Campus Study (1-6)
Grading Restriction: Satisfactory/No Credit grading only.
Repeatability: May be repeated. Maximum 6 hours.
Credit Restriction: Maximum 2 hours may be applied toward the biochemistry and cellular and molecular biology
concentration.
Registration Permission: Consent of instructor.
493 Independent Study (1-3) Independent study under the direction of a faculty member.
Repeatability: May be repeated. Maximum 12 hours.
Credit Restriction: Maximum 3 hours may be applied toward the biochemistry and cellular and molecular biology
concentration.
Registration Permission: Consent of instructor.