409 Cell Tissue and Engineering (3) Mammalian cell culture. Effects of mechanical forces on cells. Tissue engineering of cardiovascular and orthopedic devices.
(DE) Prerequisite(s): Biochemistry and Cellular and Molecular Biology 230 or Biology 140.
430 Biomedical Engineering Laboratory (3) Experience with the unique problems associated with making measurements and interpreting data in living systems. Experiments may include mechanical testing of biological materials, imaging and physiological measurements (EKG, EMG, ECG, etc.).
(DE) Prerequisite(s): 345 and Electrical and Computer Engineering 300.
473 Applied Biomechanics (3) Applications of biomechanics to the industrial and orthopedic area. Design of orthopedic implant devices; biomechanics of injury and protection.
(DE) Prerequisite(s): Mechanical Engineering 321.
(DE) Corequisite(s): 310 and Materials Science and Engineering 474.
474 Biomaterials (3) (See Materials Science and Engineering 474.)
475 Design of Artificial Internal Organs (3) Design, development and evaluation of artificial internal organs; analysis of transport processes in therapeutic devices for design optimization; current research and development needs. Ethical considerations.
(DE) Prerequisite(s): Aerospace Engineering 341 and Mathematics 231.
494 Special Project in Biomedical Engineering (1-3) Problems related to recent developments and practice.
Repeatability: May be repeated. Maximum 6 hours.
495 Special Project in Biomedical Engineering (1-3) Problems related to recent developments and practice.
Repeatability: May be repeated. Maximum 6 hours.
500 Thesis (1-15)
Grading Restriction: P/NP only.
Repeatability: May be repeated.
502 Registration for Use of Facilities (1-15) Required for the student not otherwise registered during any semester when student uses university facilities and/or faculty time before degree is completed.
Grading Restriction: Satisfactory/No Credit grading only.
Repeatability: May be repeated.
Credit Restriction: May not be used toward degree requirements.
507 Application of Linear Algebra in Engineering Systems (3) (See Chemical Engineering 507.)
509 Multidisciplinary Project (1) (See Industrial Engineering 509.)
511 Biotransport Processes (3) Cellular transport and electrical properties from a combined biological, physical, and engineering point of view. Matter transport across cellular membranes involving diffusion, osmosis, coupled solute and solvent transport, carrier-mediated transport, and ion transport. Homeostatic mechanisms involved in maintaining cellular solute concentrations, volume, and potential. Electrically inexcitable and excitable cells, lumped parameter and distributed-parameter cell models, linear electric properties of cells, and voltage gated ion channels.
(DE) Prerequisite(s): Electrical and Computer Engineering 301 or consent of instructor.
531 Advanced Biomechanics I (3) Derivation of mathematical models of the human body using Kane’s Method of Dynamics to create system equations of motions. Mathematical models will pertain to human non-implanted and implanted joints. Models will be created by hand and using the symbolic manipulation algorithm Autolev. (Same as Mechanical Engineering 531.)
(DE) Prerequisite(s): Mechanical Engineering 231.
534 Mechanical Vibrations (3) (See Mechanical Engineering 534.)
538 Ultrasonic Methods and Bioinstrumentation (3) Basic ultrasound principles including wave equation, impedance, acoustic properties of biological tissues, etc. Transducers, beam patterns, resolution, and diagnostic imaging configurations for static and dynamic real-time imaging principles. Doppler physics, Doppler spectral analysis, image quality, image artifacts, clinical safety and measurement techniques, and quality control.
Registration Permission: Consent of instructor.
539 Continuum Mechanics (3) (See Engineering Science 539.)
541 Fluid Mechanics I (3) (See Mechanical Engineering 541.)
547 Modern Linear Controls (3) (See Mechanical Engineering 547.)
548 Optimization Techniques in Biomedical Engineering (3) Current techniques in optimization. Emphasis on applying optimization techniques to problems in biomedical imaging.
Registration Permission: Consent of instructor.
552 Computational Biomechanics (3) Practical use of general-purpose commercial finite element packages for simulations related to orthopedic and sport biomechanics. Prediction of failure and performance of bone, joints and prosthetic devices.
(DE) Prerequisite(s): Mechanical Engineering 231 and 321.
555 Human Vibrations Analysis and Protection (3) Concepts of whole body vibrations, background information on the development of ANSI and ISO Standards for the protections of workers from whole body vibrations; how to apply the standards to meet the EU requirements; measurement methods and signal processing requirements for whole body vibration; background information on the development of ANSI and ISO Standards for the protections of workers for vibration white finger syndrome; development criteria for current ANSI, ISO, and EU standards; measurements methods and requirements, effectiveness of anti-vibration gloves. (Same as Aerospace Engineering 555; Mechanical Engineering 555.)
(DE) Prerequisite(s): Mechanical Engineering 363 and 534.
Registration Permission: Consent of instructor.
559 Advanced Mechanics of Materials I (3) (See Mechanical Engineering 559.)
561 Finite Elements for Engineering Applications (3) (See Engineering Science 551.)
562 Computational Fluid-Thermal Systems (3) (See Engineering Science 552.)
571 Biomechanics of Hard and Soft Tissue (3) (See Engineering Science 571.)
574 Multidimensional Medical Image Analysis (3) Applied mathematical and physical principles for different medical imaging modalities, image formation, reconstruction, enhancement and filtering, representation and analysis, registration and camera calibration models, shape and texture, transforms, features extraction, segmentation, clustering, introduction to pattern recognition and classification based on non-parametric techniques, parametric techniques, and neural networks models, 2D matching, introduction to biometrics, application in medical image segmentation, classification, and computerized medical diagnosis of diseases.
(DE) Prerequisite(s): 572, and Electrical and Computer Engineering 472.
577 Neural Networks in Engineering (3) (See Nuclear Engineering 577.)
578 Advanced Biomaterials: Biological Applications of Nanomaterials (3) (See Materials Science and Engineering 578.)
582 Micro-electromechanical Systems in Biomedical Engineering (3) Examines physical principles, design techniques, fabrication techniques, and testing technologies needed for the modern biomedical engineer working in the microfabrication field in miniaturized environments. This is a hands-on hardware and software course that includes some laboratory experiments and use of MEMS design software.
Registration Permission: Consent of instructor.
587 Dynamic Modeling and Simulation (3) (See Mechanical Engineering 587.)
588 Cell and Tissue-Biomaterials Interaction (3) (See Materials Science and Engineering 588.)
590 Selected Biomedical Engineering Problems (2-6)
Grading Restriction: Satisfactory/No Credit grading only.
Repeatability: May be repeated. Maximum 6 hours.
Comment(s): Enrollment is limited to students in the non-thesis option.
Registration Permission: Consent of instructor.
595 Seminar (1) All phases of biomedical engineering, reports on current research at UTK and UTSI.
Grading Restriction: Satisfactory/No Credit grading only.
Repeatability: May be repeated. Maximum 20 hours.
599 Special Topics in Biomedical Engineering (1-3)
Repeatability: May be repeated. Maximum 12 hours.
Registration Permission: Consent of instructor.
600 Doctoral Research and Dissertation (3-15)
Grading Restriction: P/NP only.
Repeatability: May be repeated.
610 Advanced Topics in BME (3) Current research topics of interest in biomedical engineering.
Repeatability: May be repeated. Maximum 9 hours.
Registration Permission: Consent of instructor.
611 Fields, Forces and Flows in Cells and Tissues (3) Applications of equilibrium and non-equilibrium thermodynamics to rate processes and forces in cells and tissues. Fields in heterogeneous media, electrical double layers, and electromechanical forces in physiological systems. Fluid and solid continuum mechanics of porous hydrated biological tissues. Electrophoretic, electroosmotic flows, and diffusion-reaction. Electromechanical and physicochemical interactions in biomaterials and cells. Case studies in membrane transport, electrode interfaces, electrical, mechanical, and chemical transduction in tissues. Cardiovascular, orthopedic and other clinical examples.
(DE) Prerequisite(s): 511 or consent of instructor.
631 Advanced Biomechanics II (3) Using the symbolic manipulation algorithm, difficult systems pertaining to the human body will be modeled. A more in depth analysis of Kane’s method of multibody dynamics will also be implemented in these models. Each student will focus on one complex model that pertains to an orthopedic complication that the orthopedic industry needs solved. (Same as Mechanical Engineering 631.)
(DE) Prerequisite(s): 531.
632 Biomechanics Design (3) Design of an implant, orthopaedic mechanical device, orthopaedic instrument or a rehabilitation device for a sponsoring orthopaedic company. The design project will include patent searches, literature searches and a final report.
(DE) Prerequisite(s): 531.
647 Non Linear Control Systems (3) (See Mechanical Engineering 647.)
659 Advanced Mechanics of Materials II (3) (See Mechanical Engineering 659.)
674 Neuro-Fuzzy Pattern Recognition in Medicine (3) Pattern recognition and computer vision fundamentals, human vision system, principles of image formation and human perception, camera models, sampling and quantization and image transforms. Applications of neuro-fuzzy l systems in medicine.
(DE) Prerequisite(s): 574.
682 Biological Applications of Micro and Nanoscale Systems (3) Emerging techniques in biological and biomedical research on the micro and nanoscale. Biomaterials, soft lithography, nanomedicine, microfluidic principles, sensor principles and microsensors, microactuators and drug delivery, polymerase chain reactions, and DNA microarrays.
(DE) Prerequisite(s): 582.